The effect of ouabain on sodium- and potassium-activated adenosine triphosphatase from the hearts of several mammalian species.
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چکیده
Parasympathetic Responses in Hyperthyroid Rats. ALAN FRAZER AND MARILYN E. Hess 1 The Effects of Thyroxine on Rat Heart Adenosine 3’, 5’-Monophosphate, Phosphorylace b Kinase and Phosphorylase a Activity. Ai N FRAZER, MARILYN E. HESS AND JOSEPH SHANFELD 10 The Effect of Ouabain on Sodiumand Potassium-Activated Adenosine Triphosphatase from the Hearts of Several Mammalian Species. TAI AKERA, FRAN S. LARSEN AND THEODORE M. BRODY 17 Interactions of Acetylcholine and Epinephrine on Contractility, Glycogen and Phosphorylase Activity of Isolated Mammalian Hearts. JACOB A. BLUKOO-ALLOTEY, NORMA H. VINCENT AND SIDNEY ELLIS 27 The Effect of Dipyridamole on the Metabolism of Cardiac Muscle. DM HYON YU AND M. I. GLUCEMAN 37 The Mechanism of Action of Guanethidine on the Isolated Mammalian Heart. S. PLUCHINO, A. J. MUSKUS AND R. PLUCHINO 44 Chemical Sympathectomy of the Cat with 6-Hydroxydopamine. G. HAEUSLER, W. HAEFELY AND H. THOENEN 50 Mechanism of the Sympathomimetic Action of Cyclohexylamine and Hexylamine: Release of Catecholamines from Nerve Endings. ANDHEw S. WECHSLER, STEPHEN E. EPSTEIN AND GERALD GLICK 62 Blockade of Cardiac Effects of Isoproterenol by 4-(2-Hydroxy-3-Isopropylaminopropoxy)-Acetanilide (ICI 50,172). PITAMBAR SOMANI AND ATUL R. LADDU 72 Antiarrhythmic Actions of 4-(2-Hydroxy-3-Isopropylaminopropoxy)-Acetanilide (ICI 50,172) in the Dog Heart-Lung Preparation. ATUL R. LADDU AND PITAMBAR So-
منابع مشابه
Cardiac sodium, potassium-adenosine triphosphatase as a possible site of adriamycin-induced cardiotoxicity.
Adriamycin ws tested as a possible inhibitor of cardiac sodium-potassium-activated adenosine triphosphatase (Na-K-ATPase). At concentrations of 10(-4) M and lower, Adriamycin had no effect upon either ouabain-sensitive (Na-K-ATPase) or ouabain-insensitive adenosine triphosphatase activity in homogenates and microsomal fractions of cardiac tissue from several different species. Adriamycin inhibi...
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Parasympathetic Responses in Hyperthyroid Rats. ALAN FRAZER AND MARILYN E. Hess 1 The Effects of Thyroxine on Rat Heart Adenosine 3’, 5’-Monophosphate, Phosphorylace b Kinase and Phosphorylase a Activity. Ai N FRAZER, MARILYN E. HESS AND JOSEPH SHANFELD 10 The Effect of Ouabain on Sodiumand Potassium-Activated Adenosine Triphosphatase from the Hearts of Several Mammalian Species. TAI AKERA, FRA...
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Parasympathetic Responses in Hyperthyroid Rats. ALAN FRAZER AND MARILYN E. Hess 1 The Effects of Thyroxine on Rat Heart Adenosine 3’, 5’-Monophosphate, Phosphorylace b Kinase and Phosphorylase a Activity. Ai N FRAZER, MARILYN E. HESS AND JOSEPH SHANFELD 10 The Effect of Ouabain on Sodiumand Potassium-Activated Adenosine Triphosphatase from the Hearts of Several Mammalian Species. TAI AKERA, FRA...
متن کاملRegional distribution of sodium--potassium--activated adenosine triphosphatase in the rat gastrointestinal tract.
Several solutes are preferentially absorbed by specific segments of the gastrointestinal tract(l). This variation in the distribution of sites for particular absorptive meclhanisms suggests that the enzymes related to these processes may also be assymmetrically distributed. The observation that ouabain, an inhibitor of sodium-potassium-activated adenosine triphosphatase (Na-K-ATPase) in vitro, ...
متن کاملEffects of lead and natriuretic hormone on kinetics of sodium-potassium-activated adenosine triphosphatase: possible relevance to hypertension.
Inhibition of vascular smooth muscle sodium-potassium-activated adenosine triphosphatase (Na-K-ATPase) has been postulated as a central mechanism in enhancing vascular contractility. In the present study, kinetics of inhibition of Na-K-ATPase by lead, ouabain, and natriuretic hormone (NH) was studied in a purified hog cerebral cortex enzyme preparation. Determination of I50 values for lead, oua...
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عنوان ژورنال:
- The Journal of pharmacology and experimental therapeutics
دوره 170 1 شماره
صفحات -
تاریخ انتشار 1969